Laser treatment for morphea

Laser treatment for morphea. Jun 6, 2011 · Consequently, decisions regarding morphea treatment are a complex interplay of patient age, disease subtype, disease activity, and the presence of potential or existing damage. 2 Phototherapy with 308 nm wave length, used in the excimer laser, is the most efficient wavelength for inducing DNA breakage in lymphocytes. It could be an effective, safe, and well-tolerated therapeutic method of treatment. Jun 23, 2021 · In addition, photomechanical fenestrations of the skin (vertical channels of ablation) created by fractional lasers can be used for laser-assisted drug delivery of topically applied formulation, such as PLLA, which can significantly sustain cosmetic improvement in morphea by synergistically increasing new collagen synthesis, resulting in better Keywords: morphea; localized scleroderma; laser therapy 1. Rennie, ND. The procedur e was Nov 23, 2021 · Vulvar lichen sclerosus (VLS) is a chronic inflammatory disease involving the genital skin and mucous membrane. View profile. Improved softness of skin lesions assessed by palpation was reported Scleroderma is the name for a range of conditions that affect your immune system (autoimmune conditions) and can cause hard, thickened areas of skin and sometimes problems with muscles, bones, internal organs and blood vessels. We report a previously well 7-year-old Chinese girl presenting with early facial morphea mimicking an acquired PWS with unusual Aug 7, 2023 · Topical corticosteroids are first-line treatment for superficial morphea, and the usual treatment is for 3-4 weeks. permanent eye damage in children. Win (Janet) Tcheung was board certified by the American Board of Dermatology. equally, with the average Dec 25, 2022 · Morphea and lichen sclerosus et atrophicus (LSeA) are chronic sclerotic conditions with overlapping clinicohistopathological characteristics. Morphea and lichen sclerosus et atrophicus (LSeA) are chronic sclerotic conditions with overlapping clinicohistopathological characteristics. Phototherapy, specifically UVA1, has been shown to be useful in the treatment of morphea, although the exact treatment regimen should be tailored to the Three central mechanisms seem to contribute to the effectiveness of phototherapy: breakage of DNA strands of T lymphocytes causing apoptosis, immunomodulation of the IL-6 collagen stimulating cytokine and IL-8 pro-inflammatory cytokine, and stimulus of fibroblasts to produce collagenase. org. 5 Our case demonstrates morphea-LSeA overlap in Current treatment recommendations for morphea are limited, with a combination of systemic corticosteroids and methotrexate as the most common treatment option. Morphea occurs most frequently in children aged 2-14 years, and the disease exhibits a female predominance. I see perhaps one or two cases a year. Morphea and systemic sclerosis are inflammatory, sclerosing disorders. Morphea, also known as localized scleroderma, is a chronic inflammatory disease of the dermis and subcutaneous cellular tissue in which a sclerotic process with diffuse thickening and induration of the skin is generated, as well as atrophy at various levels. Sign in | Create an account. The prescription cream calcipotriene is a synthetic form of vitamin D. Patches that gradually develop a lighter or whitish center. carbon dioxide laser therapy to improve the cosmetic effects that had been caused by the. Results: Marked clinical improvement as evidenced by improved pliability and skin coloration was seen after 4 successive PDL treatments. 3. In conclusion, this study proved that fractional Er:YAG laser is an effective treatment for morphea. 1016/j. May 5, 2021 · Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis of the skin and internal organs and has significant clinical sequelae. 2022 Dec 26;32:96-98. 34, 35 CO 2 laser has been used to treat morphea-related heel contractures, 33 digital morphea. SH. ) Postirradiation morphea — Postirradiation morphea is a rare, late complication of radiotherapy occurring months to years after treatment and is characterized by the development of sclerotic plaques that resemble Aug 12, 2016 · The vast majority of identified studies evaluated ultraviolet A1 (UVA1) phototherapy. Lichen sclerosus (LS) is a chronic inflammatory disease that mainly affects the anogenital area. 2011 Oct;147(10):1148-50. Combining ablative fractional Er:YAG laser therapy with topical methotrexate may yield therapeutic benefits for patients with LS Apr 22, 2016 · The therapeutic benefits of laser therapy with 5-FU on scars likely improve scar texture and erythema , but it is difficult to comment on the exact efficacy of the combination of laser therapy with 5-FU because of the minimal evidence available. Results Nov 14, 2023 · Diagnosis. A, Leu-koderma (or ‘‘salt and pepper’’ pigmentation) of sclero- Jul 2, 2022 · Morphea is an inflammatory, immune-mediated disease of unknown aetiology. Background: Morphea is a rare autoimmune disease characterized by excessive col-lagen deposition in skin. It is characterized by inflammation, excessive collagen production, and subsequently limited sclerosis of the skin; however, in Sep 1, 2020 · Other procedures that have been reported to be effective in the treatment of some morphea patients include photodynamic therapy and pulsed dye laser therapy for sclerotic lesions, intralesional hyaluronidase injections for morphea-induced microstomia, and extracorporeal photochemotherapy for severe, generalized disease (31,54-60). Morphea (pronounced more-FEE-ah) is a fairly unusual skin condition. Management of SSc cutaneous disease remains challenging and often is driven by extracutaneous manifestations. Office locations. Objective: We sought to create an evidence-based therapeutic algorithm. Jun 16, 2023 · Morphea is a rare autoimmune disease characterized by excessive collagen deposition in skin. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not associate Raynaud’s phenomena or sclerodactyly, which are encountered in systemic scleroderma. University Of Texas Medical Branch Galveston, 2006. 177 A 590 nm light-emitting diode system has been shown to reduce post-fractional laser erythema. Next, linear morphea participants were examined in depth over a 3-year period. For patients with more widespread lesions and deep morphea, the first-line treatment is phototherapy with ultraviolet A1 (UVA1). Broadband UVA. It is characterized by inflammation and limited thickening and induration of the skin; however, in some cases, deeper tissues might also be Aug 1, 2020 · It has been postulated that immediate improvement after treatment is related to mechanical loosening of sclerotic tissue, 33 with delayed improvements arising from tissue response and upregulation of growth factors and cytokines that modulate healing. The lesions located on the face particularly affect patients’ quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment. Morphea, or localized scleroderma, is a skin condition characterized by erythematous and indurated inflammatory lesions that progress to atrophic and sclerotic plaques. disease. 15-times higher chance of disease recurrence for an increment of 1 year in duration of morphea prior to UVA1 treatment . Scleroderma-associated dyspigmentation. It may help soften the skin patches caused by morphea. 1. It is characterized by inflammation and limited thickening and induration of the skin; however, in some cases, deeper tissues might also be Available treatments and drugs Morphea has no known cure. Morphea, also known as localized scleroderma, is a rare disease with an incidence rate of 3 in 100 000 and a prevalence rate of 50 per 100 000. Abstract. Until your condition clears up, you may want to pursue treatment that helps control your signs and symptoms. Jun 16, 2023 · Future studies should address the clinical efficacy of laser treatment; molecular mechanism; dose–response data for the laser treatment; potential synergies of laser with other treatments. LM may have a self-limited course, but it frequently has a relapsing or chronic nature despite aggressive medical treatments during the active phase of the disease. May 17, 2019 · Treatment largely depends upon the extent of disease, with minor cases of morphea requiring observation and systemic sclerosis requiring potent immunosuppressive medications. Fractional ablative lasers (FALs) are currently used for the treatment of many Apr 4, 2020 · The efficacy of excimer lasers in morphea mainly results from their anti-inflammatory action, since the 308 nm wavelength used in the excimer laser is the most efficient wavelength for inducing treatments after failure of intralesional steroid in-jections, topical calcipotriene, and MTX. However, it is considered an autoimmune disease and is associated with various predisposing factors. Morphea affects adults and children. Keywords: Morphea, Phototherapy, PUVA Aug 29, 2023 · To the best of our knowledge, there are 11 published articles reviewing the use of laser therapy in scleroderma or morphea with predominantly case reports and the largest case series involving eight patients with facial telangiectasias. 1 Treatment, including topical or systemic corticosteroids and immunosuppressive agents, can be associated with side effects and/or fail to be effective long-term, highlighting the role of alternative therapies. It's caused by an overproduction of collagen by cells in the skin called Feb 4, 2016 · In contrast, erythema that lasts beyond 1 month following ablative fractional laser treatment is considered prolonged and is seen in ~12. The patient followed the treatment plan for a full month and the white patch quickly improved for the patient. They include: Reddish or purplish oval patches of skin, often on the belly, chest or back. • Several studies have demonstrated the benefit of phototherapy for morphea confined to the cutaneous Nov 1, 2011 · A. The two main types of scleroderma are: There are also different types of localised scleroderma and systemic sclerosis. 5–7. Fractional Er:YAG laser treatment is a promising treatment to improve morphea, despite limited studies about the therapeutic effect and underlying mechanism. Due to objective symptoms as well as subjective complaints, patients with VLS experience emotional distress, lowered mood, and sexual dysfunction, which is reflected in Aug 12, 2016 · There was a 1. 2, one of the most efficient and highly recommended laser machines for Morphea treatment. With such quality, it will offer extremely adjustable, easy and friendly aesthetic operation that smoothly Jan 18, 2023 · Newer phototherapy-based therapies for morphea include laser therapy, with excimer laser being suitable for inflammatory lesions, whereas pulsed dye, alexandrite, Nd:YAG or fractional lasers are more effective for sclerotic and atrophic lesions . Treatment. The earlier you begin treatment, the more effective it is. Linear patches, especially on the arms or legs and possibly the forehead or scalp. Generalized morphea can be distingued from SSc due to lack of Fig 1. Fractional lasers. Use of a fractional ablative 10. It’s also effective at improving the appearance of acne scars. Apr 23, 2023 · Morpheus8 treatments can benefit people of all skin types and tones, addressing a broad range of skin concerns. Posligua and Hillary R. The most common form of morphea in children Morphea, also known as localized scleroderma (LoS), comprises a set of autoimmune sclerotic skin diseases. Based on the limited studies available, 20–50 J/cm 2 of UVA1 therapy 3–4 times a week for 30 treatments is recommended. No consistent recommendations exist for therapy, impeding patient care. Menu. 6-μm carbon dioxide laser in the treatment of a morphea-related contracture Arch Dermatol . The databases were searched using the relevant MeSH terms: “morphea” OR “localized scleroderma” AND “laser”. Apart from topical or oral medications, successful light-based treatments have been reported using phototherapy including Psoralen plus ultraviolet A, photodynamic therapy, carbon dioxide laser, pulsed dye Oct 22, 2022 · Localized scleroderma (LS) is an autoimmune disease with sclerosis of the skin as the main manifestation. 178 Herpes simplex virus infection is the most common infectious complication following A form of vitamin D. However, the majority of available data rely on case series and uncontrolled studies, and laser Jun 16, 2023 · Future studies should address the clinical efficacy of laser treatment; molecular mechanism; dose–response data for the laser treatment; potential synergies of laser with other treatments. Methotrexate is the typical first-line therapy for patients with early Aug 25, 2022 · Symptoms. Due to objective symptoms as well as subjective complaints, patients with VLS e … Nov 25, 2021 · Introduction. 13, 14 Thus, there are unmet needs in both understanding morphea Oct 4, 2018 · Patricia J. Treatment options vary depending on the extent of your condition and how it's affecting your life. JAAD Case Rep. eCollection 2023 Feb. Topical tacrolimus 0. Physical therapy. Sep 28, 2023 · lichen sclerosus; laser therapy; carbon dioxide laser; Neodymium:YAG laser; diode laser; systematic review. Introduction. Patients exhibit focal atrophy and destructive scarring, with an increased risk of malignant transformation. 4-2. The disease is associated with cosmetic and functional impairment, which can affect the patients’ quality of life. Laser treatment can also be helpful. Signs and symptoms of morphea vary depending on the type and stage of the condition. 1 While the pathogenesis of morphea is complex, the fibrosis in morphea is believed to be immune-driven. To our knowledge, this is the first description of excimer laser for the treatment of morphea. 1 Treatment, including topical or systemic corticosteroids and immunosuppressive agents, can be associated with side effects and/or fail to be effective long-term, highlighting the role of alternative therapies. Possible side effects include burning, stinging and a rash. Morphea, also known as localized scleroderma (LoS), comprises a set of autoimmune sclerotic skin diseases. These treatments aim to soften the skin lesions and improve cosmetic appearance. Background and Objectives: Morphea, also known as localized scleroderma, is a sclerotic inflammatory disorder that primarily affects the skin but has the potential to involve fascia, muscle and bones. When the morphea goes deeper, UVA-1 phototherapy may be prescribed. Methods: The mouse model of morphea was established by subcutaneously injecting with bleomycin (BLM). 12. 2Watt Diode Laser SIFLASER-3. Deep involvement was more common in linear (64. Background: Morphea (localized scleroderma) is a skin disorder with significant morbidity. 2022. 0 J/cm2, spot size 4 Morphea, also known as localized scleroderma (LoS), comprises a set of autoimmune sclerotic skin diseases. 1% is an alternate choice for superficial circumscribed morphea. A MEDLINE search was conducted to find articles detailing treatment of CTD with laser therapy. The effectiveness of ablative fractional laser (AFL) therapy for LS has been demonstrated in several studies. Europe PMC. It is characterised by excessive collagen deposition, which leads to the hardening of the dermis and subcutaneous tissues. 4 to 2. Coping. Jun 16, 2023 · Conclusions: We found that fractional Er:YAG laser treatment of morphea has good clinical, ultrasonic, and histopathologic efficacy, which may be a promising treatment in the future. Excimer laser therapy , which is a highly precise method for treating psoriasis and vitiligo, dermatitis and mycosis fungoides (a type of skin lymphoma) without damaging PubMed population of pediatric and adult patients diagnosed with morphea and undergoing laser treatment. It is more frequent in women, in a 3:1 or 10:1 ratio with respect to men, with a higher incidence in post-menopausal women. We present the largest cohort with a total of 23 patients having localized or diffuse sclerosis and a single The most popular approach to controlling the inflammatory phase of scleroderma is the use of immunosuppressive therapy. More rigorous studies are needed to evaluate phototherapy in the treatment of scleroderma. It involves the skin and can extend to the fascia, muscle, and bone. The search was performed in July 2021 without a date limit. In about 50% of patients the disease undergoes Dec 1, 2022 · DOI: 10. Methods: A case of plaque-type morphea was treated with 585 nm pulsed dye laser irradiation at an average fluence of 5. It excels at improving skin texture, firming mildly sagging skin, smoothing wrinkles, and minimizing other signs of aging. 2. Twelve patients with morphea were treated with low-dose (20 J/cm 2) broadband UVA 3 times a week for a total of 20 sessions . A total of 24 mice received fractional Er:YAG laser treatment once a week for 4 weeks. people per year. Methods. 823 Broad St, Durham, NC 27705. The last day to access the databases was 15 July 2021. The aim of this Cochrane Review was to assess the effects of treatments, either given in isolation or combination, for people with morphea (morphoea), when compared with an inactive substance (placebo), no intervention, any other treatment, or different doses or duration of a treatment. edu Academia. With such quality, it will offer extremely adjustable, easy and friendly Dec 26, 2022 · Introduction. doi: 10. May 1, 2022 · Morphea is an inflammatory, immune-mediated disease of unknown aetiology. It often only affects the outer layer of skin but sometimes leads to more serious issues due to the involvement of deeper parts of the body. Phototherapy with ultraviolet light is capable of decreasing inflammation and may also have immunomodulatory effects. edu no longer supports Internet Explorer. 0 J/cm2 at bimonthly time intervals. Education. Fig 2. Mar 9, 2020 · Introduction. They have been misdiagnosed as acquired port-wine stains (PWSs). The generalized mor-phea subtype is defined as $4 morphea plaques occurring over $2 anatomic sites. Additional studies are needed to clarify its efficacy with 5-FU, as there is insufficient evidence Nov 6, 2023 · (See "Laser and light therapy for cutaneous vascular lesions" and "Laser and light therapy for cutaneous hyperpigmentation". cosmetic deformities. Fractional ablative carbon dioxide laser therapy can be considered as a promising option for patients suffering from morphea. 2011. Morphea usually lasts several years and then goes away without treatment. Use of a 585 nm Pulsed Dye Laser for the Treatment of Morphea (PDF) Use of a 585 nm Pulsed Dye Laser for the Treatment of Morphea | Daniel Eisen and Tina Alster - Academia. Results: Linear morphea was the most common morphea subtype (50. In this model, the fibrosis is an “innocent bystander” that is driven by the cytokines aluminum garnet (Er:YAG) laser for the treatment of morphea in mouse model. • We are reporting the use of excimer laser for active sclerotic morphea plaques. A moisturizer with camphor and menthol can help cool your skin and relieve itch. 1,4. Plaque type morphea. Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. 2 is one of the most effective and widely used laser equipment for Morphea therapy. Treatment of morphea focuses on controlling the signs and symptoms and slowing the spread of the disease. Gold-tipped microneedles stimulate the skin’s natural healing response to generate new skin cells Jun 16, 2023 · Fractional Er:YAG laser treatment is a promising treatment to improve morphea, despite limited studies about the therapeutic effect and underlying mechanism. Jul 30, 2021 · Photodynamic Therapy in the Treatment of Vulvar Lichen Sclerosus: A Systematic Review of the Literature Previous Article in Journal A Novel Method for Adjusting the Taper and Adaption of Automatic Tooth Preparations with a High-Power Femtosecond Laser Feb 8, 2024 · The patient was managed with topical therapies and phototherapy, which are commonly used treatments for morphea (1). The fractional lasers mode of action is depend on fractional photo thermolysis which means generating in the skin a mesh of micro thermal treatment zones surrounded by healthy, undamaged tissue. Morphea plaque of our patient after 16 treatments A strong corticosteroid like prednisone can treat large calcium deposits that develop beneath the skin. No side effects or complications were encountered. 2Watt LASER-3. Smidt}, journal={JAAD Case Reports Nov 2, 2021 · Vulvar lichen sclerosus (VLS) is a chronic inflammatory disease involving the genital skin and mucous membrane. Treatment options to mitigate disease progression remain limited. 5% of patients. About 20% of patients can develop extracutaneous features including arthritis, uveitis, and seizures. 18 years of experience. UVA-1 produces long Apr 4, 2020 · Localized superficial morphea can be treated with the excimer laser (using ultraviolet type B light, in range of 308nm) if topical steroid administration shows no significant clinical improvement. It is characterized by Oct 27, 2020 · leading to hardened fibrotic skin changes. By targeting different depths, from the epidermis to the dermis to the subdermis, the technology creates a more toned complexion. The mouse model of morphea was established by subcutaneously injecting with bleomycin Nov 11, 2020 · Background: Linear morphea is a variant of scleroderma limited to the skin and underlying tissues secondary to an autoimmune inflammation leading to excess collagen deposition and fibrosis. https://orcid. Currently, there is no specific treatment for LS. Review question. The Smart Medical Diode Laser 26. In addition, try a warm (not hot) bath with baby oil or oatmeal to soothe your skin. 2 The average age of onset for Methods: Characteristics of linear morphea versus other subtypes were compared in a cross-sectional manner. 7 cases per 100,000. A number of conditions that predominantly occur in women and that have a paucity of effective treatments include rosacea, connective tissue disease, melasma, nevus of Ota, lichen sclerosus (LS), notalgia paresthetica and macular amyloidosis, and syringomas. For treatment of morphea lesions excimer are used sucessfully Carbon Dioxide (CO2) or Erbium Doped Yttrium Aluminum Garnet (Er:YAG). 005 Corpus ID: 255172413; Excimer laser treatment for morphea-lichen sclerosus et atrophicus overlap in a pediatric patient @article{Hong2022ExcimerLT, title={Excimer laser treatment for morphea-lichen sclerosus et atrophicus overlap in a pediatric patient}, author={Emily Hong and Alba L. The exact cause of morphea is unknown. After completing this learning activity, participants will be able to review cutaneous manifestations of systemic sclerosis and morphea, including en coup de sabre and progressive hemifacial atrophy, and discuss the physiological and psychological burden of these diseases; discuss and compare different laser treatments, injectables, and May 14, 2020 · Keeping the lesions moisturized can help relieve itching. 1-3 Usually, its evolution is benign; however, 10 % of patients suffer severe sclerosis and atrophy, which can cause Dec 26, 2022 · Excimer laser treatment for morphea-lichen sclerosus et atrophicus overlap in a pediatric patient. Morphea primarily affects the dermis and subcutaneous fat, while systemic sclerosis typically involves the skin and internal organs. This device possesses 4 wavelengths: 635nm, 810nm, 980nm and 1064nm with Maximum power up to 26. Case 1: A 50-year-old man with biopsy-proven linear morphea of right parietofrontal scalp/forehead presented with concerns about facial asymmetry with expressions and hyperpigmentation related to his condition. Morphea on the top layers of your skin: A type of light treatment called narrowband UVB treatment can be helpful. Further Mar 19, 2022 · This device is called the Smart Medical 26. 1%, 291/581) in the cohort. Introduction Morphea, also known as localized scleroderma (LoS), encompasses a spectrum of autoimmune cutaneous connective tissue diseases. Morphea, also sometimes called “localized scleroderma,” is a rare autoimmune disorder that causes skin thickening, hardening, and color changes. Jul 30, 2021 · https://orcid. 4 In a young woman with morphea unresponsive to topical ste-roids and MTX, 17 excimer treatments combined with hydroxychloroquine and topical calcipotriene/ betamethasone resolved peripheral erythema. This case series explores the outcomes of 2 patients with a diagnosis of morphea after treatment with deep fractionated CO 2 laser. jdcr. Insights into morphea pathogenesis are often extrapolated from Apr 28, 2020 · Morphea and systemic sclerosis are inflammatory, sclerosing disorders. The rationale is that an autoimmune process is causing the inflammation and the downstream result is tissue damage and fibrosis. joint pain. Choose a thick cream rather than a lotion, and apply it twice a day for best results. Both functional impairment and cosmetic deficits Dec 27, 2023 · A treatment was proposed involving immunosuppressants, methotrexate, and pimecrolimus cream along with topical corticosteroids and excimer laser therapy (308 nm). The early inflammatory lesions of morphea may present with erythema or violaceous patches and plaques before evolving into areas of sclerosis. The precise treatment depends on the extent and severity of your condition, but may include: Aug 1, 2002 · To review the use of laser therapy in the treatment of LE, scleroderma, sarcoidosis, and dermatomyositis. Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0. Despite the large number of reported therapies (ie, phototherapy, systemic immunosuppressives, and topical preparations), no consistent recommendations exist for therapy Jul 17, 2021 · Current treatment recommendations for morphea are limited, with a combination of systemic corticosteroids and methotrexate as the most common treatment option. 2 A recent study showing the anti-fibrotic effects of the phosphodiesterase 4 (PDE4) inhibitor apremilast in 2 days ago · Win (Janet) Tcheung, MD is a Dermatologist in Durham, NC. It may leave scars or areas of darkened or discolored skin. 3%, 187/291) than aluminum garnet (Er:YAG) laser for the treatment of morphea in mouse model. 1001/archdermatol. To our knowledge, this is the first description of excimer laser used for the treatment of morphea. 6 Generalized morphea. 2 Phototherapy with ultraviolet A1 Sep 1, 2017 · Laser treatment is a relatively new and increasingly popular modality for the treatment of many dermatologic conditions. About. Although an exhaustive discussion of medical therapies for this spectrum of diseases is beyond the scope of this chapter, surgeries and laser therapy are important UVA-1 is an innovative light therapy for many skin conditions, including scleroderma, morphea and cutaneous graft-versus-host disease (GVHD), which is not commonly available. Methods: We reviewed English-language literature using search engines and hand searches for therapeutic Jul 30, 2021 · A systematic review of available literature using lasers in morphea identified a total of twenty relevant studies using laser therapy for LoS and focused on the use of PDL, six on fractional lasers, four on excimer, and two on either alexandrite or Nd:YAG. 247. FAL therapy decreases dermal thickness, increases elasticity, and improves the clinical appearance of morphea lesions. 6 times more than men, and can appear in all races, though appears to be more common, up to 73-82%, among Caucasians. Interventions for morphea. Elwood and Aimee C. The plaque type — which is the most common and probably what your wife has — affects women more often than it does men and typically is seen on the trunk. Jul 1, 2021 · The underlying etiology of LM is still poorly understood, although some have suggested that morphea represents a mosaic form of systemic sclerosis limited to the skin 1. 005. About Europe Sep 2, 2020 · Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. 5, 9, 10 However, these are not disease-specific treatments and their long-term use is associated with many side effects. 13, 14 Thus, there are unmet needs in both understanding morphea No of the Patients Patients Morphea Duration of Type of Laser No of Additional Study Type of Study Age Parameters Results of Treatment Adverse Effects Completing Type Disease Used Treatments Therapy [Years] the Study wavelength 585 nm long-pulsed, fluence Softening and Eisen Pulsed dye laser Case report 1 41 Plaque - 5. Jul 30, 2021 · Laser Therapy for the Treatment of Morphea: A Systematic Review of Literature. 2Watt. Functional impairment and cosmetic disfigurement are common in both diseases. About Europe PMC; Preprints in Europe PMC . Jul 1, 2002 · Other procedures that have been reported to be effective in the treatment of some morphea patients include photodynamic therapy and pulsed dye laser therapy for sclerotic lesions, intralesional The Morpheus8 laser combines microneedling with radiofrequency energy to address skin laxity for a lifted look. Localized scleroderma or morphea, an autoimmune disorder, is the most common form of scleroderma in children. hair loss Jan 3, 2024 · Morphea scleroderma is a skin condition characterized by hardened, discolored, and thickened patches of skin on various areas of the body without internal organ involvement. Skin generally begins to improve during the first months of treatment. 1 The disease affects women 2. Jul 7, 2017 · Morphea with deep lesions, lesions on your face or neck, or widespread lesions can lead to: restricted joint mobility. The incidence of morphea is 0. ei hy kq fy vl xc ar zc pn nr